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4-hydroxyestrone-4-methyl ether

CAS No. 58562-33-7

4-hydroxyestrone-4-methyl ether( 4-Methoxy Estrone )

Catalog No. M28697 CAS No. 58562-33-7

4-hydroxyestrone-4-methyl ether is the methylation of 4-OHE1, which is catalyzed by COMT.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
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Biological Information

  • Product Name
    4-hydroxyestrone-4-methyl ether
  • Note
    Research use only, not for human use.
  • Brief Description
    4-hydroxyestrone-4-methyl ether is the methylation of 4-OHE1, which is catalyzed by COMT.
  • Description
    4-hydroxyestrone-4-methyl ether is the methylation of 4-OHE1, which is catalyzed by COMT.(In Vitro):4-hydroxyestrone-4-methyl ether(10 and 100 nM) increases the proliferation of human umbilical vein endothelial cells (HUVECs).
  • In Vitro
    ——
  • In Vivo
    ——
  • Synonyms
    4-Methoxy Estrone
  • Pathway
    Endocrinology/Hormones
  • Target
    Estrogen Receptor/ERR
  • Recptor
    Apoptosis
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    58562-33-7
  • Formula Weight
    599.78
  • Molecular Formula
    C38H47O6
  • Purity
    >98% (HPLC)
  • Solubility
    ——
  • SMILES
    C[C@](CC1)([C@@H](CC2)[C@H](CC3)[C@H]1c(cc1)c3c(OC)c1O)C2=OC[C@](CC1)([C@@H](CC2)[C@H](CC3)[C@H]1c(cc1)c3c(OC)c1O)C2=O
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.Salehi AH, et, al. AEG3482 is an antiapoptotic compound that inhibits Jun kinase activity and cell death through induced expression of heat shock protein 70. Chem Biol. 2006 Feb;13(2):213-23.
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